понеделник, 7 януари 2013 г.
Why women gain weight with age
Although we strive hard to maintain normal weight, one of the worst things that come with age, is gaining extra pounds.
Scientists discovered the link between weight and age for the fair sex.
After menopause, the activity of an enzyme playing a major role in the production of fat increases.
Also known as Aldh1a1, the enzyme is reason to accumulate more dangerous fat around organs, known as visceral fat.
This can cause the development of type 2 diabetes, heart disease and cancer and is produced by the enzyme accumulates mainly in women when consuming a high fat meal.
Researchers at Ohio State University found that female hormone estrogen suppresses the effects of dangerous bacteria.
The downside is that when women are in menopause, hormone levels decrease dramatically, and Aldh1a1 is free to rampage in the body, leading to weight gain.
Focusing on Aldh1a1, professionals can develop new treatments against obesity in women, said assistant professor of human nutrition at Ohio State University - Ziozenkova oils.
To test whether the accumulation of visceral fat has to do with estrogen levels in women, the researchers surgically removed the ovaries of mice.
If animals could no longer produce estrogen their bodies started to produce retinoic acid, which leads to the formation of visceral fat.
"It appears that estrogen protects female mice from obesity-related hormones or junk food," says Dr. Ziozenkova.
"This means that estrogen inhibits the activation of hormones associated with obesity, and as soon as women enter menopause, visceral fat starts to increase," the investigator continued.
The study was published in the January issue of the journal Diabetes, reported Daily Mail.